It is the least demanding assisted reproduction method, where washed and concentrated sperm are applied to the woman’s uterus directly using a thin plastic catheter at the time of ovulation. The advantage is its easy and non-invasive procedure without the need for anesthesia. It is particularly suitable for couples where the man has a good or borderline count of motile sperm, or the woman has reduced cervical mucus permeability (negative postcoital test).

The success rate of this method is around 10%.

Donor sperm can also be used for insemination if needed.

The use of this method allows the selection of high-quality sperm for artificial fertilization based on their movement through a thin membrane with channels, mimicking the natural movement of sperm through the female reproductive tract. The advantage of microfluidic separation chips is that centrifugation is not required for sperm processing, which minimizes mechanical damage to the sperm and their DNA. Motile, viable sperm travel through the channels into the collection well of the chip and are then used for artificial fertilization.

Single-use separation chips are especially recommended in cases of poor oocyte fertilization, poor embryo development in previous IVF cycles, or after recurrent miscarriages. The method cannot be used if the ejaculate volume is insufficient or if there is a reduced number of progressively motile sperm in the ejaculate.

This is a micromanipulation fertilization technique, in which a sperm is injected into a mature egg using a micropipette (a thin glass needle).
It is a very precise and effective method used in indicated cases and is essential in cases of pathological sperm analysis.

This is a method in which spontaneous fertilization of the egg occurs after adding a specific amount of purified sperm to the medium containing the egg. The sperm then swim actively with their tails to reach the egg, penetrate it, and fertilize it. It is particularly suitable when sperm quality is good.

A laser is used to open the embryo’s outer shell – the zona pellucida. This disruption facilitates the embryo’s hatching and implantation in the uterine lining. It is a gentle procedure that does not damage the internal structures of the embryo. In standard cases, the embryo hatches on its own; assisted hatching is only appropriate in indicated cases.

It is a special medium for embryo transfer. Its key component is hyaluronan, which is a natural part of the uterine environment. Literature indicates that women over 35 often have a deficiency of hyaluronan in the uterine environment. Therefore, adding it through the special Embryo Glue medium facilitates easier implantation of the embryo in the uterine lining.